Publications & Expertise

The staff of the proteomics core work closely with customers, and are often heavily involved in the write-up process of projects that have made use of mass spectrometry services. In addition to our co-authored papers, our work is frequently acknowledged by our researchers in their publications and our work has been essential toward many researchers obtaining grants. If you are a customer of the core, and have published work that made use of the proteomics services that we offer, we’d like to list your publication here. Please contact us with details.

Selected Recent Customer & Collaborator Publications

2026

EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization.
Gong L, Liu X, Yang X, Yu Z, Bhat MY, Chen S, Lemoff A, Xing C, Liu X.
Nat Commun. 2026, PMID: 41519789

Phosphoproteomics identification of ERK-dependent activation of Rps6kb1 in cardiac hypertrophy.
Li C, Zhang P, Zhang K, Cook JA, Song W, Virostek M, Slotabec LA, Rouhi N, Hazari M, Adenawoola MI, Liu X, Zhang H, Zhang G, Niewold EL, Li Q, Fang Y, Elhelaly WM, Sun XN, Guo X, Lemoff A, Deng Y, Gillette TG, Li J, Scherer PE, Wang ZV.
JCI Insight. 2026, PMID: 41505219

KDM5A methylation modulates its genomic demethylase and transcriptional actions.
Tran TA, Gopinathan G, Nuñez CG, Goodavish F, Wu SY, Tran R, Lemoff A, Girard L, Martinez ED.
J Biol Chem. 2026, PMID: 41962864

A shared amyloid fold in cardiac fibrils from three neuropathy-associated ATTR variants.
Fernandez-Ramirez MDC, Afrin S, Nguyen BA, Singh V, Pękala M, Singh P, Ahmed Y, Pedretti R, Lemoff A, Kluve-Beckerman B, Chhapra F, Eisenberg D, Saelices L.
Structure. 2026, PMID: 41734755

Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice.
Savani MR, Li B, Smith BC, Gu W, Xiao Y, Baquer G, Shipman T, Oken SS, Manoj N, Zacharias LG, Puliyappadamba VT, Stopka SA, Regan MS, Levitt MM, Edgar CK, Hicks WH, Anand S, Martin-Sandoval MS, Winston R, S Patrício J, Johnson X, Tippetts TS, Shi DD, Lemoff A, Richardson TE, Zinn PO, Solmonson A, Mathews TP, Agar NYR, DeBerardinis RJ, Abdullah KG, McBrayer SK.
Nat Metab. 2026, PMID: 42056505

Structural polymorphism of ex-vivo ALECT2 amyloid fibrils revealed by cryo-EM.
Afrin S, Nguyen BA, Singh V, Singh P, Bassett P, Pekala M, Evers B, Lopez C, Ahmed Y, Li L, Kallem RR, Lemoff A, Argyropoulos C, Kluve-Beckerman B, Saelices L.
Nat Commun. 2026, PMID: 41965342

Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations.
Nguyen BA, Fernandez-Ramirez MDC, Bassett P, Singh V, Singh P, Pękała M, Villalon L, Ahmed Y, Lemoff A, Evers B, Lopez C, Kluve-Beckerman B, Saelices L.
Nat Commun. 2026, PMID: 41991931

Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122Δ amyloidosis.
Ahmed Y, Nguyen BA, Kelly C, Afrin S, Singh V, Evers BM, Shelton JM, Lopez Escobar C, Singh P, Pedretti R, Wang L, Bassett P, Fernandez-Ramirez MDC, Pekala M, Lemoff A, Kluve-Beckerman B, Saelices L.
Commun Biol. 2026, PMID: 41917523

2025

Mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism.
Kim D, Kesavan R, Ryu K, Dey T, Marckx A, Menezes C, Praharaj PP, Morley S, Ko B, Soflaee MH, Tom HJ, Brown H, Vu HS, Tso SC, Brautigam CA, Lemoff A, Mettlen M, Mishra P, Cai F, Allen DK, Hoxhaj G.
Nat Cell Biol. 2025, PMID: 40258949

VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea J, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI.
Mol Neurodegener. 2025, PMID: 39773263

Cryo-EM structure and regulation of human NAD kinase.
Praharaj PP, Li Y, Mary C, Soflaee MH, Ryu K, Kim D, Tran DH, Dey T, Tom HJ, Rion H, Gelin M, Lemoff A, Zacharias LG, Patricio JS, Mathews TP, Chen Z, Lionne C, Hoxhaj G, Labesse G.
Sci Adv. 2025, PMID: 39854463

Regulation of food intake by Connexin43 via adipocyte-sensory neuron electrical synapses.
Chen X, Fang X, Zhou H, Meng J, He Y, Straub LG, Lemoff A, Crewe C, Zhao S, Xu Y, Zhu Y.
Mol Metab. 2025, PMID: 40915562

The yeast Mkt1/Pbp1 complex promotes adaptive responses to respiratory growth.
Caballero D, Sutter BM, Xing Z, Wang C, Choo E, Wang Y, Yang YS, Ghaemmaghami S, Lemoff A, Tu BP.
J Cell Biol. 2025, PMID: 40801888

Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle.
Sacharidou A, Chambliss KL, Peng J, Tanigaki K, Islam MN, Sirsi S, Lemoff A, Hoyt K, Mineo C, Shaul PW.
Mol Metab. 2025, PMID: 40907945

MS Proteomics Services