2026<\/strong><\/p>\nEPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization.
\nGong L, Liu X, Yang X, Yu Z, Bhat MY, Chen S, Lemoff A, Xing C, Liu X.
\nNat Commun. 2026, PMID: 41519789<\/p>\n
Phosphoproteomics identification of ERK-dependent activation of Rps6kb1 in cardiac hypertrophy.
\nLi C, Zhang P, Zhang K, Cook JA, Song W, Virostek M, Slotabec LA, Rouhi N, Hazari M, Adenawoola MI, Liu X, Zhang H, Zhang G, Niewold EL, Li Q, Fang Y, Elhelaly WM, Sun XN, Guo X, Lemoff A, Deng Y, Gillette TG, Li J, Scherer PE, Wang ZV.
\nJCI Insight. 2026, PMID: 41505219<\/p>\n
KDM5A methylation modulates its genomic demethylase and transcriptional actions.
\nTran TA, Gopinathan G, Nu\u00f1ez CG, Goodavish F, Wu SY, Tran R, Lemoff A, Girard L, Martinez ED.
\nJ Biol Chem. 2026, PMID: 41962864<\/p>\n
A shared amyloid fold in cardiac fibrils from three neuropathy-associated ATTR variants.
\nFernandez-Ramirez MDC, Afrin S, Nguyen BA, Singh V, P\u0119kala M, Singh P, Ahmed Y, Pedretti R, Lemoff A, Kluve-Beckerman B, Chhapra F, Eisenberg D, Saelices L.
\nStructure. 2026, PMID: 41734755<\/p>\n
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice.
\nSavani MR, Li B, Smith BC, Gu W, Xiao Y, Baquer G, Shipman T, Oken SS, Manoj N, Zacharias LG, Puliyappadamba VT, Stopka SA, Regan MS, Levitt MM, Edgar CK, Hicks WH, Anand S, Martin-Sandoval MS, Winston R, S Patr\u00edcio J, Johnson X, Tippetts TS, Shi DD, Lemoff A, Richardson TE, Zinn PO, Solmonson A, Mathews TP, Agar NYR, DeBerardinis RJ, Abdullah KG, McBrayer SK.
\nNat Metab. 2026, PMID: 42056505<\/p>\n
Structural polymorphism of ex-vivo ALECT2 amyloid fibrils revealed by cryo-EM.
\nAfrin S, Nguyen BA, Singh V, Singh P, Bassett P, Pekala M, Evers B, Lopez C, Ahmed Y, Li L, Kallem RR, Lemoff A, Argyropoulos C, Kluve-Beckerman B, Saelices L.
\nNat Commun. 2026, PMID: 41965342<\/p>\n
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations.
\nNguyen BA, Fernandez-Ramirez MDC, Bassett P, Singh V, Singh P, P\u0119ka\u0142a M, Villalon L, Ahmed Y, Lemoff A, Evers B, Lopez C, Kluve-Beckerman B, Saelices L.
\nNat Commun. 2026, PMID: 41991931<\/p>\n
Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122\u0394 amyloidosis.
\nAhmed Y, Nguyen BA, Kelly C, Afrin S, Singh V, Evers BM, Shelton JM, Lopez Escobar C, Singh P, Pedretti R, Wang L, Bassett P, Fernandez-Ramirez MDC, Pekala M, Lemoff A, Kluve-Beckerman B, Saelices L.
\nCommun Biol. 2026, PMID: 41917523<\/p>\n
2025<\/strong><\/p>\nMitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism.
\nKim D, Kesavan R, Ryu K, Dey T, Marckx A, Menezes C, Praharaj PP, Morley S, Ko B, Soflaee MH, Tom HJ, Brown H, Vu HS, Tso SC, Brautigam CA, Lemoff A, Mettlen M, Mishra P, Cai F, Allen DK, Hoxhaj G.
\nNat Cell Biol. 2025, PMID: 40258949<\/p>\n
VCP regulates early tau seed amplification via specific cofactors.
\nBatra S, Vaquer-Alicea J, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI.
\nMol Neurodegener. 2025, PMID: 39773263<\/p>\n
Cryo-EM structure and regulation of human NAD kinase.
\nPraharaj PP, Li Y, Mary C, Soflaee MH, Ryu K, Kim D, Tran DH, Dey T, Tom HJ, Rion H, Gelin M, Lemoff A, Zacharias LG, Patricio JS, Mathews TP, Chen Z, Lionne C, Hoxhaj G, Labesse G.
\nSci Adv. 2025, PMID: 39854463<\/p>\n
Regulation of food intake by Connexin43 via adipocyte-sensory neuron electrical synapses.
\nChen X, Fang X, Zhou H, Meng J, He Y, Straub LG, Lemoff A, Crewe C, Zhao S, Xu Y, Zhu Y.
\nMol Metab. 2025, PMID: 40915562<\/p>\n
The yeast Mkt1\/Pbp1 complex promotes adaptive responses to respiratory growth.
\nCaballero D, Sutter BM, Xing Z, Wang C, Choo E, Wang Y, Yang YS, Ghaemmaghami S, Lemoff A, Tu BP.
\nJ Cell Biol. 2025, PMID: 40801888<\/p>\n
Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle.
\nSacharidou A, Chambliss KL, Peng J, Tanigaki K, Islam MN, Sirsi S, Lemoff A, Hoyt K, Mineo C, Shaul PW.
\nMol Metab. 2025, PMID: 40907945<\/p>\n","protected":false},"excerpt":{"rendered":"
The staff of the proteomics core\u00a0work closely with customers, and are often heavily involved in the write-up process of projects that have made use of mass spectrometry services. In addition to our co-authored papers, our work is frequently acknowledged by our researchers in their publications and our work has been essential toward many researchers obtaining … Continue reading Publications & Expertise<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":29,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/pages\/39"}],"collection":[{"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=39"}],"version-history":[{"count":34,"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions"}],"predecessor-version":[{"id":1719,"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions\/1719"}],"up":[{"embeddable":true,"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=\/wp\/v2\/pages\/29"}],"wp:attachment":[{"href":"https:\/\/proteomics.swmed.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=39"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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The staff of the proteomics core\u00a0work closely with customers, and are often heavily involved in the write-up process of projects that have made use of mass spectrometry services. In addition to our co-authored papers, our work is frequently acknowledged by our researchers in their publications and our work has been essential toward many researchers obtaining grants. If you are a customer of the core, and have published work that made use of the proteomics services that we offer, we’d like to list your publication here. Please contact us with details.<\/p>\n