Publications
2007Yu, P. and Kodadek, T. (2007) “Dynammics of the Hypoxia-Inducible
Factor-1-VEGF promoter complex” Submitted.
Lim, H.-S., Cai, D. and Kodadek, T. (2007) “Chemical cross-linking
reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor
of the 19S proteasome regulatory particle” Submitted.
Udugamasooriya, D.G., Dineen, S.P., Brekken, R.A. and Kodadek, T.
(2007) “A peptoid ‘antibody surrogate’ that antagonizes VEGF Receptor
2 activity” Submitted.
Sikder, D. and Kodadek, T. (2007) “The neurohormone orexin stimulates
hypoxia-inducible factor-1 activity” Submitted.
Kwon, Y.-U. and Kodadek, T. (2007) “Quantitative comparison
of the relative cell permeability of cyclic and linear peptides”
Chem. & Biol.
14, 671-677.
Lim, H.-Y., Archer, C.T. and Kodadek, T. (2007) “Identification
of a peptoid inhibitor of the proteasome 19S regulatory particle”
J. Amer. Chem. Soc. 129, 7750-7751.
Yu, P. and Kodadek, T. (2007) “A convenient, high-throughput strategy
for measuring the relative cell permeability of synthetic compounds”
Nature Protocols 2, 23-30.
Kwon, Y.-U. and Kodadek, T. (2007) “Quantitative evaluation of the
relative cell permeability of peptoids and peptides”J. Amer. Chem.
Soc. 129, 1508-1509.
2006
Page, T., Sikder, D. Yang, L. Pluta, L., Wolfinger, R.D., Kodadek,
T. and Thomas, R.S. (2006) Genome-wide analysis of human HSF1 signaling
reveals a transcriptional program linked to cellular adaptation and
survival” Molecular BioSystems, 2, 627-639.
Sikder, D., Johnston, S.A. and Kodadek, T. (2006) “Widespread, but
non-identical, association of proteasomal 19S and 20S proteins with
yeast chromatin” J. Biol. Chem. 281, 27346-27355.
Kodadek, T., Sikder, D. and Nalley, K. (2006) “Keeping transcriptional
activators under control” Cell 127, 261-264.
Nalley, K., Johnston, S.A. and Kodadek, T. (2006) “Proteolytic turnover
of Gal4 is not required for function in vivo” Nature 442, 1054-1057.
Sikder, K. and Kodadek, T. (2006) “Optimized protocols for the isolation
of specific protein-binding peptides or peptoids from combinatorial
libraries displayed on beads” Molecular BioSystems 2, 25-35.
2005
Reddy, M.M. and Kodadek, T. (2005) “Protein ‘fingerprinting’ in
complex mixtures using peptoid microarrays” Proc. Natl. Acad. Sci.
USA 102, 12672-12677.
Li, S., Marthandan, N., Bowerman, D., Garner, H.R. and Kodadek,
T. (2005) Photolithographic synthesis of cyclic peptide arrays using
a differential deprotection strategy” Chem. Comm., 581-583.
Sikder, D. and Kodadek, T. (2005) “Genomic studies of transcription
factor-DNA interactions” Curr. Opin. Chem. Biol. 9, 38-45.
2004
Kodadek, T., Reddy, M.M., Olivos, H.J., Bachhawat-Sikder , K. and
Alluri, P.G. (2004) “Synthetic molecules as antibody replacements”
Acc. Chem. Res. 37, 711-718.
Moola, R., Bacchawat –Sikder, K. and Kodadek, T. (2004) “Transformation
of low affinity lead compounds into high affinity protein
capture agents”Chem. & Biol. 11, 1127-37.
Li, S., Bowerman, D.J., Marthandan, N., Garner, H.R. and Kodadek,
T. (2004) “Photolithographic synthesis of peptoids” J. Amer. Chem.
Soc. 126, 4088-4089.
Smith, A.H., Vrtis, J.M. and Kodadek, T. (2004) “The Potential of
Protein-Detecting Microrrays for Clinical Diagnostics” Clinical Chem
37, 217-238.
Troitskaya, L. and Kodadek, T. (2004) “Peptides as modulators of
enzymes and regulatory proteins”Methods 32, 406-415.
2003
Bacchawat-Sikder, K. and Kodadek, T. (2003) “Protein detecting microarrays
for diagnostics and basic research”Clin. Lab. Intl. 27, 16-18.
Alluri, P.G. Reddy, M.M., Bacchawat-Sikder, K., Olivos, H.J. and
Kodadek, T. (2003) “Isolation of protein ligands from large peptoid
libraries” J. Amer. Chem. Soc. 125, 13995-14004.
Olivos, H.J., Bacchawat-Sikder, K. and Kodadek, T. (2003) “Quantum
dots as a visual aid for screening bead-bound combinatorial libraries”
ChemBiochem 4, 1242-1245.
Sikder, K. and Kodadek, T. (2003) “Mixed Element Capture Agents
(MECAs): A Simple Strategy For the Construction of Synthetic, High
Affinity Protein Capture Ligands” J. Amer. Chem. Soc. 125, 9550-9551.
Naffin, J.L., Han, Y. Sun, T., Reddy, M.M., Olivos, H.J., and
Kodadek, T. (2003) “Immobilized peptides as high affinity capture
agents for
self-associating proteins” Chem. & Biol. 10, 251-259.